Concepedia

PP2A mediates diosmin p53 activation to block HA22T cell proliferation and tumor growth in xenografted nude mice through PI3K–Akt–MDM2 signaling suppression

Tran Duc Dung, Cecilia Hsuan Day, Truong Viet Binh, Chih-Hsueh Lin, Hsi-Hsien Hsu, Cheng‐Chuan Su, Yueh-Min Lin, Fuu‐Jen Tsai, Wei‐Wen Kuo, Li-Mien Chen,

Food and Chemical Toxicology · 2012 · 49 citations · 26 references

DOI

Concepts

References

26

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

Michael N. Berry, Daniel S. Friend · The Journal of Cell Biology · 1969 · 4.4K citations · Full text

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein et al. · PubMed · 1994 · 3.5K citations

, , +16

Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2

Muyang Li, Christopher Brooks, Foon Wu-Baer et al. · Science · 2003 · 794 citations

, , +9

The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

Paolo Neviani, Ramasamy Santhanam, Rossana Trotta et al. · Cancer Cell · 2005 · 472 citations · Full text

, , +13

In Vivo Mitochondrial p53 Translocation Triggers a Rapid First Wave of Cell Death in Response to DNA Damage That Can Precede p53 Target Gene Activation

Susan Erster, Motohiro Mihara, Roger H. Kim et al. · Molecular and Cellular Biology · 2004 · 368 citations · Full text

, , +17