Concepedia

Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death

Maria Høyer-Hansen, Lone Bastholm, Ida Stenfeldt Mathiasen, Folmer Elling, Marja Jäättelä

Cell Death and Differentiation · 2005 · 247 citations · 43 references

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43

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

Xiao Huan Liang, Saadiya Jackson, Matthew Seaman et al. · Nature · 1999 · 3.3K citations

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat et al. · Journal of Clinical Investigation · 2003 · 2.2K citations · Full text

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Zhenyu Yue, Chingwen Yang, Arnold J. Levine et al. · Proceedings of the National Academy of Sciences · 2003 · 2.1K citations · Full text

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3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Per O. Seglen, Paul B. Gordon · Proceedings of the National Academy of Sciences · 1982 · 1.3K citations · Full text

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