Neurology · 1980 · 49 citations · 0 references
MedicineInternal MedicineNeurologyNeurocritical CareNeurodegenerationNeuropathologyCerebrovascular DiseaseStrokeSystemic Lupus ErythematosusThrombosisThrombotic DisordersVenous ThromboembolismCardiovascular InvolvementCerebral Arterial SupplyCerebral InjuryClonic SeizuresNeurologic Involvement In VasculitisSeizuresSystemic Lupus Erythematosus Associations
Left homonymous hemianopia, hemiparesis, left-body clonic seizures, and progressive deterioration of consciousness complicated the clinical course of a 57-year-old woman with systemic lupus erythematosus (SLE). Autopsy documented the presence of multiple brain infarcts and cerebral arterial emboli that originated from the verrucae of Libman-Sacks endocarditis. Clinicians and pathologists should consider this unusual vascular mechanism of cerebral injury in patients with SLE who develop strokes.