Polyethylenimine with acid-labile linkages as a biodegradable gene carrier

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

Engineering, In Vivo Gene Therapy, Several Polycations +20

A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos · Journal of Biomedical Materials Research · 1999 · 817 citations

Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine

Klaus Kunath · Journal of Controlled Release · 2003 · 797 citations

Dna Nanotechnology, Engineering, Low-molecular-weight Polyethylenimine +9

Characterization of commercially available and synthesized polyethylenimines for gene delivery

Anke von Harpe, Holger Petersen, Youxin Li et al. · Journal of Controlled Release · 2000 · 505 citations

Engineering, Polymer-drug Conjugate, Polymer Science +6