Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXP

Left-handed Polyproline II Helices Commonly Occur in Globular Proteins

Alexei A. Adzhubei, Michael J.E. Sternberg · Journal of Molecular Biology · 1993 · 466 citations

Protein Function, Protein Assembly, Protein Folding +4

Activation of Phosphatidylinositol-3′ Kinase by Src-Family Kinase SH3 Binding to the p85 Subunit

Christopher M. Pleiman, W. Hertz, John C. Cambier · Science · 1994 · 435 citations

Molecular Regulation, Molecular Biology, Cellular Physiology +19

Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Dieter Seebàch, M. BOES, Reto Naef et al. · Journal of the American Chemical Society · 1983 · 390 citations

Derivative (Chemistry), Engineering, Amino Acids +13

Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase.

Christopher M. Pleiman, Marcus R. Clark, Lisa K. Timson Gauen et al. · Molecular and Cellular Biology · 1993 · 156 citations · Full text

Immunology, Molecular Biology, Cytoskeleton +19

Protein Structure-Based Combinatorial Chemistry:  Discovery of Non-Peptide Binding Elements to Src SH3 Domain

Andrew P. Combs, Tarun M. Kapoor, Sibo Feng et al. · Journal of the American Chemical Society · 1996 · 87 citations

Protein Assembly, Biomolecular Structure Prediction, Structural Bioinformatics +22