Concepedia

Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway

Arianna Nencini, Carmela Pratelli, Joanna Quinn, Massimiliano Salerno, Patrizia Tunici, Alessandra De Robertis, Silvia Valensin, Federica Mennillo, Marco Rossi, Annette Bakker,

European Journal of Medicinal Chemistry · 2015 · 19 citations · 34 references

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References

34

Wnt signaling and cancer

Paul Polakis · Genes & Development · 2000 · 3.2K citations · Full text

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Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang, Yuji Mishina, Shanming Liu et al. · Nature · 2009 · 2.1K citations

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Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Baozhi Chen, Michael Dodge, Wei‐Jen Tang et al. · Nature Chemical Biology · 2009 · 1.4K citations · Full text

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Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 835 citations · Full text

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Wnt/β-Catenin Is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells

Tea Fevr, Sylvie Robine, Daniel Louvard et al. · Molecular and Cellular Biology · 2007 · 638 citations · Full text

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