Arianna Nencini

siRNA screen identifies QPCT as a druggable target for Huntington's disease

María Jiménez-Sánchez, Wun Lam, Michael Hannus et al. · Nature Chemical Biology · 2015 · 93 citations · Full text

Druggable Target, Genetics, Molecular Biology +2

Identification and Characterization of a Small-Molecule Inhibitor of Wnt Signaling in Glioblastoma Cells

Alessandra De Robertis, Silvia Valensin, Marco Rossi et al. · Molecular Cancer Therapeutics · 2013 · 51 citations · Full text

Wnt Signaling, Cancer Biology, Glioma +20

Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)

Chiara Ghiron, Simon N. Haydar, Suzan Aschmies et al. · Journal of Medicinal Chemistry · 2010 · 30 citations · Full text

Brain Penetration, Pharmacotherapy, Medicinal Chemistry +18

Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)

Riccardo Zanaletti, Laura Bettinetti, Cristiana Castaldo et al. · Journal of Medicinal Chemistry · 2012 · 26 citations · Full text

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor

Arianna Nencini, Cristiana Castaldo, Thomas A. Comery et al. · European Journal of Medicinal Chemistry · 2014 · 21 citations

Biochemistry, Medicine, Nicotine +5