Piperine, a plant alkaloid of the piper species, enhances the bioavailability of aflatoxin B1 in rat tissues

Glutathione S-Transferases

William H. Habig, M. Pabst, William B. Jakoby · Journal of Biological Chemistry · 1974 · 18.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.

C.K. Atal, Raghvendra K. Dubey, Jatinder Singh · Journal of Pharmacology and Experimental Therapeutics · 1985 · 353 citations

Pharmacy, Biochemistry, Pharmacology +17

Aflatoxin B1-2,3-oxide: Evidence for its formation in rat liver and by human liver microsomes

David H. Swenson, Elizabeth C. Miller, James A. Miller · Biochemical and Biophysical Research Communications · 1974 · 213 citations

Veterinary Medicine, Biochemistry, Toxicology +14

Inhibition of drug metabolism. I. Kinetics of the inhibition of the N-demethylation of ethylmorphine by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and related compounds.

M.W. Anders, Gilbert J. Mannering · PubMed · 1966 · 196 citations

Life Sciences, Biochemistry, Pharmacology +15

Piperine-mediated inhibition of glucuronidation activity in isolated epithelial cells of the guinea-pig small intestine: evidence that piperine lowers the endogeneous UDP-glucuronic acid content.

Jaswant Singh, Raghvendra K. Dubey, C.K. Atal · Journal of Pharmacology and Experimental Therapeutics · 1986 · 113 citations

Medicine, Biochemistry, Pharmacology +12