Effects of MK-801 and antidepressant drugs in the forced swimming test in rats

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Medicine, Pharmacology, Psychiatry +17

Behavioural despair in rats: A new model sensitive to antidepressant treatments

Roger D. Porsolt, Guy Anton, N. Blavet et al. · European Journal of Pharmacology · 1978 · 3.1K citations

Medicine, Behavioral Sciences, Neurobiology +13

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

Ramón Trullás, P. Skolnick · European Journal of Pharmacology · 1990 · 777 citations

Medicine, Neuroscience, Pharmacology +12

Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity

Roger D. Porsolt, Anne Bertin, N. Blavet et al. · European Journal of Pharmacology · 1979 · 577 citations

Medicine, Neuroscience, Pharmacology +14