High-level generation of polyclonal antibodies by genetic immunization

Initial sequencing and analysis of the human genome

Eric S. Lander, Lauren Linton, Bruce W. Birren et al. · Nature · 2001 · 24.6K citations · Full text

Life Sciences, Genetics, Human Development +10

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Hitoshi Niwa, Ken‐ichi Yamamura, Jun‐ichi Miyazaki · Gene · 1991 · 5.2K citations

Life Sciences, Biotechnology, Molecular Biology +15

Genetic immunization is a simple method for eliciting an immune response

De‐chu C. Tang, Michael J. DeVit, Stephen Albert Johnston · Nature · 1992 · 1.5K citations

Life Sciences, Genetics, Immunology +8

Synthesis and assembly of hepatitis B virus surface antigen particles in yeast

Pablo Valenzuela, Angélica Medina, William J. Rutter et al. · Nature · 1982 · 875 citations

Life Sciences, Microbiology, Molecular Biology +9

Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

Willem P.C. Stemmer, Andreas Crameri, Kim D. Ha et al. · Gene · 1995 · 731 citations

Life Sciences, Biotechnology, Molecular Biology +15