Relationship between the rate of reductase-cytochrome P450 complex formation and the rate of first electron transfer

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

Y. Yasukochi, Bettie Sue Siler Masters · Journal of Biological Chemistry · 1976 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Studies on the Rate of Reduction of Hepatic Microsomal Cytochrome P-450 by Reduced Nicotinamide Adenine Dinucleotide Phosphate: Effect of Drug Substrates

Philippe L. Gigon, Theodore E. Gram, James R. Gillette · Molecular Pharmacology · 1969 · 291 citations

Medicine, Biochemistry, Pharmacology +17

Separation and purification of multiple forms of microsomal cytochrome P-450. Partial characterization of three apparently homogeneous cytochromes P-450 prepared from livers of phenobarbital- and 3-methylcholanthrene-treated rats

F. Peter Guengerich · Journal of Biological Chemistry · 1978 · 254 citations · Full text

Medicine, Biochemistry, Pharmacology +8

Temperature dependence of cytochrome P-450 reduction. A model for NADPH-cytochrome P-450 reductase:cytochrome P-450 interaction.

J.A. Peterson, Richard E. Ebel, David H. O’Keeffe et al. · Journal of Biological Chemistry · 1976 · 241 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +12

Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system.

John S. French, F. Peter Guengerich, Minor J. Coon · Journal of Biological Chemistry · 1980 · 226 citations · Full text

Medicine, Biochemistry, Pharmacology +17