Hormonal requirements for the induction of cytochrome P450 in hepatocytes cultured in a serum-free medium

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition.

S. Granick, Peter Sinclair, Shigeru Sassa et al. · Journal of Biological Chemistry · 1975 · 305 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits

Yoshio Imai, Ryo Sato · Biochemical and Biophysical Research Communications · 1974 · 305 citations

Medicine, Biochemistry, Pharmacology +12

Maintenance of cytochrome P-450 and metabolism of aflatoxin B1 in primary hepatocyte cultures

Gary M. Decad, D.P.H. Hsieh, James L. Byard · Biochemical and Biophysical Research Communications · 1977 · 177 citations

Life Sciences, Biochemistry, Toxicology +15

Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process.

Shigeru Sassa, Attallah Kappas · Journal of Biological Chemistry · 1977 · 160 citations · Full text

Life Sciences, Biochemistry, Endocrinology +14