A single amino acid of the cholecystokinin-B/gastrin receptor determines specificity for non-peptide antagonists

Rapid and efficient site-specific mutagenesis without phenotypic selection.

Thomas A. Kunkel · Proceedings of the National Academy of Sciences · 1985 · 7.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

Patricia L. Faris, Barry R. Komisaruk, Linda R. Watkins et al. · Science · 1983 · 582 citations

Medicine, Neuroscience, Pharmacology +17

Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist.

Robert S. Chang, Victor J. Lotti · Proceedings of the National Academy of Sciences · 1986 · 542 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Expression cloning and characterization of the canine parietal cell gastrin receptor.

A S Kopin, Y M Lee, Edward W. McBride et al. · Proceedings of the National Academy of Sciences · 1992 · 509 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Brain and gastrointestinal cholecystokinin receptor family: structure and functional expression.

Stephen A. Wank, Joseph R. Pisegna, Andreas de Weerth · Proceedings of the National Academy of Sciences · 1992 · 445 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16