Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.8K citations

Medicine, Cell Biology, Physiology +17

Iron-Overload–Related Disease in<i>HFE</i>Hereditary Hemochromatosis

Katrina J. Allen, Lyle C. Gurrin, Clare C. Constantine et al. · New England Journal of Medicine · 2008 · 724 citations · Full text

Medicine, Genetics, Hematology +16

Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis

Kim R. Bridle, David M. Frazer, Sarah J. Wilkins et al. · The Lancet · 2003 · 617 citations

Medicine, Genetics, Molecular Medicine +14

Hepcidin is decreased in TFR2 hemochromatosis

Elizabeta Nemeth, Antonella Roetto, Giovanni Garozzo et al. · Blood · 2004 · 398 citations · Full text

Medicine, Molecular Biology, Pathology +10

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

Vera Niederkofler · Journal of Clinical Investigation · 2005 · 371 citations · Full text

Medicine, Biochemistry, Molecular Genetics +17