Concepedia

Synthesis of 2-[3-(7-Chloro-quinolin-4-ylamino)-alkyl]-1-(substituted phenyl)-2,3,4,9-tetrahydro-1H-β-carbolines as a new class of antimalarial agents

Leena Gupta, Kumkum Srivastava, Shubhra Singh, S.K. Puri, Prem M. S. Chauhan

Bioorganic & Medicinal Chemistry Letters · 2008 · 75 citations · 20 references

DOI

Concepts

References

20

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

Ric N. Price, Anne‐Catrin Uhlemann, Alan Brockman et al. · The Lancet · 2004 · 839 citations

, , +13

Chloroquine Resistance in <i>Plasmodium falciparum</i> Malaria Parasites Conferred by <i>pfcrt</i> Mutations

Amar Bir Singh Sidhu, Dominik Verdier-Pinard, David A. Fidock · Science · 2002 · 715 citations · Full text

, , +16

DRUG SENSITIVITY OF PLASMODIUM FALCIPARUM

Karl H. Rieckmann, Gary H. Campbell, L. J. Sax et al. · The Lancet · 1978 · 513 citations

, , +9

The Wider World

JohnA. Loraine · The Lancet · 1974 · 358 citations

Structure−Function Relationships in Aminoquinolines:  Effect of Amino and Chloro Groups on Quinoline−Hematin Complex Formation, Inhibition of β-Hematin Formation, and Antiplasmodial Activity

Timothy J. Egan, Roger Hunter, Catherine H. Kaschula et al. · Journal of Medicinal Chemistry · 1999 · 311 citations

, , +10