Loss of cftr function leads to pancreatic destruction in larval zebrafish

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

Lutz Nährlich, Jochen G. Mainz, Constantin Adams et al. · Cellular Physiology and Biochemistry · 2013 · 2.5K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Simple and highly efficient BAC recombineering using galK selection

Søren Warming · Nucleic Acids Research · 2005 · 1.3K citations · Full text

Life Sciences, Biotechnology, Genetics +17

Evidence for Periciliary Liquid Layer Depletion, Not Abnormal Ion Composition, in the Pathogenesis of Cystic Fibrosis Airways Disease

Hirotoshi Matsui, Barbara R. Grubb, Robert Tarran et al. · Cell · 1998 · 1.2K citations · Full text

Veterinary Medicine, Pathobiology, Physiology +13

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

Natural Sciences, Cell Biology, Molecular Biology +17