Proangiogenic Effects of Protease-Activated Receptor 2 Are Tumor Necrosis Factor-α and Consecutively Tie2 Dependent - Concepedia

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Proangiogenic Effects of Protease-Activated Receptor 2 Are Tumor Necrosis Factor-α and Consecutively Tie2 Dependent

39

Citations

27

References

2006

Year

Tang Zhu, Florian Sennlaub, Martin Beauchamp, Li Fan, Jean Sebastian Joyal, Daniella Checchin, Satra Nim, Pierre Lachapelle, Mirna Sirinyan, Xin Hou,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

The proangiogenic properties of PAR2 are intertwined with its proinflammatory effects, such that in retinal vasculature, they depend on TNF-alpha and subsequent induction of tie2 via the MEK/ERK pathway.

References

	Year	Citations

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