Concepedia

Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy

Emilie Collmann, Thomas Bohnacker, Romina Marone, Janet Dawson, Markus Rehberg, Rowan Stringer, Fritz Krombach, Christoph Burkhart, Emilio Hirsch, Gregory J. Hollingworth,

Journal of Allergy and Clinical Immunology · 2013 · 36 citations · 38 references

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38

Mast-Cell Infiltration of Airway Smooth Muscle in Asthma

Christopher E. Brightling, Peter Bradding, Fiona A. Symon et al. · New England Journal of Medicine · 2002 · 1.2K citations · Full text

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Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation

Emilio Hirsch, Vladimir L. Katanaev, Cecília Garlanda et al. · Science · 2000 · 1.2K citations

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses

Alexandre Arcaro, Matthias P. Wymann · Biochemical Journal · 1993 · 1.1K citations · Full text

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Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot et al. · Science · 2002 · 937 citations

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Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil et al. · Molecular and Cellular Biology · 1996 · 680 citations · Full text

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