Concepedia

Tandem Chain Extension-Homoenolate Formation:  The Formation of α-Methylated-γ-Keto Esters

Ramona Hilgenkamp, Charles K. Zercher

Organic Letters · 2001 · 29 citations · 11 references

DOI

Concepts

Abstract

A tandem chain extension-homoenolate formation reaction is described. The treatment of beta-keto esters with the Furukawa reagent followed by exposure to a catalytic amount of trimethylsilyl chloride provides access to an ester homoenolate. Reaction: see text.

References

11

Synthesis of cyclopropanes by the reaction of olefins with dialkylzinc and methylene iodide

Junji Furukawa, Nariyoshi Kawabata, Jun Nishimura · Tetrahedron · 1968 · 406 citations

, , +4

Novel free radical ring-expansion reactions

Paul Dowd, Soo-Chang Choi · Tetrahedron · 1989 · 121 citations

, , +7

Observation of plasmon frequency in the optical spectrum of Au18Ag20 cluster: the beginning of the collective phenomenon characteristics of the bulk?

Boon K. Teo, Kelly A. Keating, Y. H. Kao · Journal of the American Chemical Society · 1987 · 104 citations

, , +9

Topological selectivity in the intramolecular [4 + 1] pyrroline annulation. Formal total stereospecific synthesis of (.+-.)-supinidine, (.+-.)-isoretronecanol, and (.+-.)-trachelanthamidine

Tomáš Hudlický, J. O. FRAZIER, Gustavo Seoane et al. · Journal of the American Chemical Society · 1986 · 91 citations

, , +8

A receptor for the oriented binding of uric acid type molecules

T. Ross Kelly, Martin P. Maguire · Journal of the American Chemical Society · 1987 · 82 citations

, , +14