J. O. FRAZIER

Topological selectivity in the intramolecular [4 + 1] pyrroline annulation. Formal total stereospecific synthesis of (.+-.)-supinidine, (.+-.)-isoretronecanol, and (.+-.)-trachelanthamidine

Tomáš Hudlický, J. O. FRAZIER, Gustavo Seoane et al. · Journal of the American Chemical Society · 1986 · 91 citations

Topological Selectivity, Biochemistry, Donut Icon +12

Intramolecular [4 + 1] pyrroline annulation approach to pyrrolizidine alkaloids. Formal total synthesis of (±)-supinidine.

Tomáš Hudlický, J. O. FRAZIER, L. D. KWART · Tetrahedron Letters · 1985 · 46 citations

Bioorganic Chemistry, Engineering, Medicine +8

Regioselectivity in the Reformatskii reaction of 4-bromocrotonate. Role of the catalyst and the solvent in the normal vs. abnormal modes of addition to carbonyl substrates

Leonard E. Rice, M Boston, Harry O. Finklea et al. · The Journal of Organic Chemistry · 1984 · 46 citations

Abnormal Modes, Asymmetric Catalysis, Molecular Sciences +13

Heteroatom cyclopentene annulation. Synthesis of guaiane ring system

Tomáš Hudlický, Serengulam V. Govindan, J. O. FRAZIER · The Journal of Organic Chemistry · 1985 · 31 citations

Heterocyclic, Guaiane Ring System, Donut Icon +8

General Methodology for the Topologically Selective Preparation of Linear and Nonlinear Tricyclopentanoids of Hirsutane and Isocomene Type<i>via</i>a Claisen Rearrangement / Cyclopentene Annulation Sequence. Total Synthesis of (±)- Epiisocomene

Tomáš Hudlický, L. D. KWART, M. TIEDJE et al. · Synthesis · 1986 · 22 citations

Chemical Engineering, Medicinal Chemistry, Engineering +15