Malignant Transformation of Lymphadenosis Benigna Cutis: A Possibly Transformed Case and B‐cell Lymphoma

Abstract

Abstract This study presents a patient who had had a 10 year history of lymphadenosis benigna cutis (LABC) before malignant lymphoma of the skin subsequently developed. During the LABC stage, the lesion showed several foci of cavernous hemangioma‐like nodules which disappeared spontaneously but reccurred repeatedly. These cutaneous nodules were finally diagnosed as malignant lymphoma of the skin with a histology of diffuse, mixed small and large cell type according to the classification of the Working Formulation. Among the subpopulations of tumor cells, B‐cells were highly predominant. It is suggested that LABC may have the potential to transform into malignant lymphoma (probably B‐cell lymphoma).