Concepedia

Tamoxifen activates CYP3A4 and MDR1 genes through steroid and xenobiotic receptor in breast cancer cells

Rin Nagaoka, Toshiharu Iwasaki, Nana Rokutanda, Akira Takeshita, Yukio Koibuchi, Jun Horiguchi, Noriaki Shimokawa, Yuichi Iino, Yasuo Morishita, Noriyuki Koibuchi

Endocrine · 2006 · 33 citations · 33 references

DOI

Concepts

References

33

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

, , +9

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer

Sarah L. Anzick, Juha Kononen, Robert L. Walker et al. · Science · 1997 · 1.7K citations

, , +17

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

Molecular Determinants for the Tissue Specificity of SERMs

Yongfeng Shang, Myles Brown · Science · 2002 · 1.1K citations

, , +17

Luciferase reporter gene vectors for analysis of promoters and enhancers.

SK Nordeen · PubMed · 1988 · 1K citations

, , +12