Publication | Closed Access
Formation of the (R)- and (S)-enantiomers of ethyl 3-hydroxybutanoate and of 1-(1,3-dithian-2-yl)-2-hydroxypropane by microbial reduction
19
Citations
0
References
1984
Year
Bioorganic ChemistryEngineeringOrganic ChemistryBiosynthesisDifferent StrainsNatural Product BiosynthesisStereoselective SynthesisGeotrichum CandidumBiotransformationPharmacologyNatural Product SynthesisEnantioselective SynthesisBiomolecular EngineeringAspergillus NigerAntifungal AgentMicrobial ReductionMicrobiologyMedicineSynthetic Chemistry
The (R)and (S) enantiomers of 3-hydroxybutanoate [(2a) or (3a)] and 1-(1,3-dithian-2-yl)-2-hydroxypropane [(2b) or (3b)] are obtained from ethyl 3-oxobutanoate (1a) and 1-(1,3-dithian-2-yl)-2-oxopropane (1b), respectively, using growing cultures from different strains of Geotrichum candidum and Aspergillus niger.