Treatment of Type II Gastric Carcinoid Tumors with Somatostatin Analogues

Abstract

Gastric carcinoid tumors are rare tumors that originate from gastric enterochromaffin-like cells in the oxyntic mucosa.1 There are three types of gastric carcinoid tumors: type I is associated with chronic atrophic gastritis, type II develops in patients with combined multiple endocrine neoplasia type 1 and the Zollinger–Ellison syndrome, and type III is sporadic.1 Although the pathogenesis of these tumors is not completely understood, hypergastrinemia has an important role in the development of types I and II.2 The multiple endocrine neoplasia type 1 gene locus may be involved in type II gastric carcinoid tumors.3,4 All three types are usually removed . . .