Concepedia

Piperazine derivatives including the putative anxiolytic drugs, buspirone and ipsapirone, are agonists at 5-HT1A receptors negatively coupled with adenylate cyclase in hippocampal neurons

Jo�l Bockaert, Aline Dumuis, Rochdi Bouhelal, Mich�le Sebben, RobertN. Cory

Naunyn-Schmiedeberg s Archives of Pharmacology · 1987 · 139 citations · 24 references

DOI

Concepts

References

24

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Précis of<i>The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system</i>

Jeffrey A. Gray · Behavioral and Brain Sciences · 1982 · 4.5K citations

, , +13

A highly sensitive adenylate cyclase assay

Yoram Salomon, Constantine Londos, Martin Rodbell · Analytical Biochemistry · 1974 · 4.2K citations

, , +8

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

, , +17