Concepedia

Involvement of MicroRNA-133a in the Development of Arteriosclerosis Obliterans of the Lower Extremities via RhoA Targeting

Yongxin Li, Mao Ouyang, Zhen Shan, Jieyi Ma, Jie Li, Chen Yao, Zhengrong Zhu, Longjuan Zhang, Lianzhou Chen, Guangqi Chang,

Journal of Atherosclerosis and Thrombosis · 2014 · 16 citations · 21 references

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Abstract

Our data indicate that miR-133a regulates the functions of HASMCs by targeting RhoA and may be involved in the pathogenesis of ASO. These findings may lead to the development of potential therapeutic targets for ASO of the lower extremities.

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