Evidence for megalin-mediated proximal tubular uptake of L-FABP, a carrier of potentially nephrotoxic molecules

An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

Duska Dragun, Diego J. Walther, Henrik Vorum et al. · Cell · 1999 · 1K citations · Full text

Medicine, Biochemistry, Endocrinology +16

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

A J Levi, I. M. Arias · Journal of Clinical Investigation · 1969 · 597 citations · Full text

Medicine, Biochemistry, Pharmacology +10

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.

Akihiko Saito, Salvatore F. Pietromonaco, A K Loo et al. · Proceedings of the National Academy of Sciences · 1994 · 565 citations

Life Sciences, Biochemistry, Molecular Biology +15

Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors α- and γ-mediated gene expression via liver fatty acid binding protein: A signaling path to the nucleus

Christian Wolfrum, Carola M. Borrmann, Torsten Börchers et al. · Proceedings of the National Academy of Sciences · 2001 · 505 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.

Thomas E. Willnow, J L Goldstein, Kim Orth et al. · Journal of Biological Chemistry · 1992 · 466 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17