Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

Michael A. Curran, Welby Montalvo, Hideo Yagita∥ et al. · Proceedings of the National Academy of Sciences · 2010 · 1.9K citations · Full text

Life Sciences, Immunology, Oncology +17

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Laura A. Johnson, Richard A. Morgan, Mark E. Dudley et al. · Blood · 2009 · 1.4K citations · Full text

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Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

Keiji Hirota, Hiroyuki Yoshitomi, Motomu Hashimoto et al. · The Journal of Experimental Medicine · 2007 · 924 citations · Full text

Medicine, Immunology, Pathology +13

The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

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Life Sciences, Immunology, Molecular Biology +16

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

Jacqueline D. Shields, Iraklis C. Kourtis, Alice A. Tomei et al. · Science · 2010 · 501 citations · Full text

Medicine, Immunology, Oncology +17