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Reassessing the melatonin pharmacophore—Enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue

Molecular PharmacologyMelatonin Pharmacophore—enantiomeric ResolutionEnantioselective SynthesisStructure AnalysisBiochemistryMedicineDrug DiscoveryRational Drug DesignPharmacological ActivityPharmacologyPharmaceutical ChemistryMelatoninPharmacodynamic Modeling