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Inhibition of von Willebrand factor‐mediated platelet activation and thrombosis by the anti‐von Willebrand factor A1‐domain aptamer ARC1779

Daniel Duerschmied, Yahye Merhi, J.F. TANGUAY, Renta Hutabarat, Jean Charles Gilbert, Denisa D. Wagner, Robert G. Schaub, John L. Diener, H. A. Daniel Lagassé

Journal of Thrombosis and Haemostasis · 2009 · 152 citations · 29 references

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References

29

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

Louis C. Bock, Linda C. Griffin, John Latham et al. · Nature · 1992 · 2.5K citations

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Structures of Glycoprotein Ibα and Its Complex with von Willebrand Factor A1 Domain

Eric G. Huizinga, Shizuko Tsuji, Roland A. Romijn et al. · Science · 2002 · 551 citations · Full text

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First-in-Human Evaluation of Anti–von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers

James C. Gilbert, Tia DeFeo-Fraulini, Renta Hutabarat et al. · Circulation · 2007 · 285 citations · Full text

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Crystal Structure of the von Willebrand Factor A1 Domain and Implications for the Binding of Platelet Glycoprotein Ib

Jonas Emsley, Miguel A. Crúz, Robert I. Handin et al. · Journal of Biological Chemistry · 1998 · 259 citations · Full text

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Early Increase of von Willebrand Factor Predicts Adverse Outcome in Unstable Coronary Artery Disease

Gilles Montalescot, Philippe François, Annick Ankri et al. · Circulation · 1998 · 253 citations · Full text

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