Antioxidant Capacity of Lipid Nanoparticles Loaded with Rosemary Extract

Abstract

This work presents a simple, available and effective method for preparation of lipid nanoparticles loaded with a natural extract containing active principles. The purpose of the research is to synthesize new lipid nanoparticles with enhanced antioxidant activity, by using two types of lipid carriers. The lipid nanoparticles were produced by emulsification with high shear homogenisation method using biocompatible emulsifiers with excellent skin compatibility as surfactants. The developed nanoparticles were characterized for particle size, polydispersity index, zeta potential, morphology, crystallinity of the lipid matrices and antioxidant activity. Both types of synthesized lipid nanoparticles exhibit an improved antioxidant activity.