The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

Paul A. Erickson, J Gao, KS Chang et al. · Blood · 1992 · 574 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

Jianxiang Wang, Taizo Hoshino, Robert L. Redner et al. · Proceedings of the National Academy of Sciences · 1998 · 522 citations

Life Sciences, Genetics, Molecular Biology +17

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1‐MTG8 fusion transcript.

Hiroyuki Miyoshi, T Kozu, Kimiko Shimizu et al. · The EMBO Journal · 1993 · 513 citations · Full text

Medicine, Molecular Biology, Oncology +14

Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO

Vania Gelmetti, Jinsong Zhang, Mirco Fanelli et al. · Molecular and Cellular Biology · 1998 · 498 citations

Life Sciences, Molecular Biology, Oncology +17

ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors

Bart Lutterbach, Jennifer J. Westendorf, Bryan Linggi et al. · Molecular and Cellular Biology · 1998 · 440 citations · Full text

Life Sciences, Molecular Biology, Oncology +15