Down-regulation of amyloid precursor protein by peptide nucleic acid oligomer in cultured rat primary neurons and astrocytes

Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide

Peter E. Nielsen, Rolf H. Berg, Ole Buchardt · Science · 1991 · 3.3K citations

Dna, Engineering, Achiral Polyamide Backbone +22

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 735 citations

Bioorganic Chemistry, Peptide Engineering, Altmetric Attention Score +17

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

Margus Pooga, Ursel Soomets, Mattias Hällbrink et al. · Nature Biotechnology · 1998 · 569 citations

Inflammation, Pain Transmission, Galanin Receptor Levels +15

The Intracellular Domain of the β-Amyloid Precursor Protein Is Stabilized by Fe65 and Translocates to the Nucleus in a Notch-like Manner

W. Taylor Kimberly, Jessica B. Zheng, Suzanne Y. Guénette et al. · Journal of Biological Chemistry · 2001 · 437 citations · Full text

Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro.

Bernadette Allinquant, Philippe Hantraye, Pierre Mailleux et al. · The Journal of Cell Biology · 1995 · 247 citations · Full text

Neurodegenerative Diseases, Vector Peptide, Molecular Neuroscience +14