IEEE Transactions on Medical Imaging · 2014 · 107 citations · 27 references
MedicineNuclear MedicineRadiologyBiomedical ImagingDiagnostic ImagingDiagnostic RadiologyAttenuation CorrectionImage ReconstructionImagingMedical ImagingPositron Emission TomographyPositron Emission Tomography PhysicsAttenuation Coefficient EstimationAttenuation FactorsMaximum Likelihood EstimatorPet Attenuation CorrectionPet Image ReconstructionPositron Emission Tomography ReconstructionScale Factor EstimationTime-of-flight Pet
In positron emission tomography (PET), attenuation correction is typically done based on information obtained from transmission tomography. Recent studies show that time-of-flight (TOF) PET emission data allow joint estimation of activity and attenuation images. Mathematical analysis revealed that the joint estimation problem is determined up to a scale factor. In this work, we propose a maximum likelihood reconstruction algorithm that jointly estimates the activity image together with the sinogram of the attenuation factors. The algorithm is evaluated with 2-D and 3-D simulations as well as clinical TOF-PET measurements of a patient scan and compared to reference reconstructions. The robustness of the algorithm to possible imperfect scanner calibration is demonstrated with reconstructions of the patient scan ignoring the varying detector sensitivities.
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Attenuation correction for a combined 3D PET/CT scanner
Paul E. Kinahan, D.W. Townsend, Thomas Beyer et al. · Medical Physics · 1998 · 933 citations
Physical and clinical performance of the mCT time-of-flight PET/CT scanner
Bjoern Jakoby, Yanic Bercier, Maurizio Conti et al. · Physics in Medicine and Biology · 2011 · 483 citations