Enhanced radiosensitivity of non-small-cell lung cancer (NSCLC) by adenovirus-mediated ING4 gene therapy

Cancer Statistics, 2009

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2009 · 9.7K citations · Full text

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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors

Benjamin J. Moeller, Yiting Cao, Chuan Y. Li et al. · Cancer Cell · 2004 · 978 citations

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Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

John Brognard, Amy S. Clark, Yucheng Ni et al. · PubMed · 2001 · 892 citations

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Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.

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Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas.

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