Disruption of the Cr2 Locus Results in a Reduction in B-1a Cells and in an Impaired B Cell Response to T-Dependent Antigen

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Victor L. J. Tybulewicz, C. Crawford, Peter K. Jackson et al. · Cell · 1991 · 1.3K citations

Medicine, Genetics, Molecular Biology +15

Defective B cell development and function in Btk-deficient mice

Wasif N. Khan, Frederick W. Alt, Rachel M. Gerstein et al. · Immunity · 1995 · 727 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

CD19: Lowering the Threshold for Antigen Receptor Stimulation of B Lymphocytes

Robert H. Carter, Douglas T. Fearon · Science · 1992 · 676 citations

Life Sciences, Cell Biology, Immunology +14

Impairment of T-cell-dependent B-cell responses and B-l cell development in CD19-deficient mice

Robert C. Rickert, Klaus Rajewsky · Nature · 1995 · 667 citations

Life Sciences, Developmental Biology, Immunology +16