Trypsin display on the surface of bacteriophage

Rapid and efficient site-specific mutagenesis without phenotypic selection.

Thomas A. Kunkel · Proceedings of the National Academy of Sciences · 1985 · 7.3K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

By-passing immunization

James D. Marks, Hennie R. Hoogenboom, Timothy P. Bonnert et al. · Journal of Molecular Biology · 1991 · 1.6K citations

Antibody-selectable filamentous fd phage vectors: affinity purification of target genes

Stephen Parmley, George P. Smith · Gene · 1988 · 871 citations

Engineering, Bioengineering, Biotechnology +16

Converting Trypsin to Chymotrypsin: The Role of Surface Loops

Lizbeth Hedstrom, László Szilágyi, William J. Rutter · Science · 1992 · 470 citations

Life Sciences, Biochemistry, Molecular Biology +17

Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces.

Angray S. Kang, Carlos F. Barbas, Kim D. Janda et al. · Proceedings of the National Academy of Sciences · 1991 · 414 citations

Pharmacy, Bioengineering, Biotechnology +17