HDAC Activity Is Required for p65/RelA-Dependent Repression of PPARδ-Mediated Transactivation in Human Keratinocytes

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

Life Sciences, Cell Biology, Immunology +10

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

Gabriel Pascual, Amy L. Fong, Sumito Ogawa et al. · Nature · 2005 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

Bart Staels, Wolfgang Köenig, Régine Merval et al. · Nature · 1998 · 1.1K citations

Life Sciences, Molecular Biology, Pharmacology +14

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

Philippe Delerive, Karolien De Bosscher, Sandrine Besnard et al. · Journal of Biological Chemistry · 1999 · 1.1K citations · Full text

Life Sciences, Cell Biology, Physiology +17

15-Deoxy-Δ ^12,14 -prostaglandin J ₂ inhibits multiple steps in the NF-κB signaling pathway

Daniel S. Straus, Gabriel Pascual, Mei Li et al. · Proceedings of the National Academy of Sciences · 2000 · 1K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13