Structure-affinity relationships of berbines or 5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizines at α-adrenoceptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

CXIX.—The formation and stability of spiro-compounds. Part I. spiro-Compounds from cyclohexane

Richard Moore Beesley, Christopher Kelk Ingold, Jocelyn Field Thorpe · Journal of the Chemical Society Transactions · 1915 · 722 citations

Natural Sciences, Chemistry, Organic Chemistry +4

Carbon-13 magnetic resonance. VII. Steric perturbation of the carbon-13 chemical shift

David M. Grant, B. Vernon Cheney · Journal of the American Chemical Society · 1967 · 580 citations

Natural Sciences, Chemistry, Analytical Chemistry +6

Studies on the relationship between chemical constitution and physiological action

Leslie Hilton Easson, Edgar Stedman · Biochemical Journal · 1933 · 447 citations · Full text

Natural Sciences, Chemistry, Physiology +6

Binding characteristics of 3H-prazosin to rat brain α-adrenergic receptors

Pamela Greengrass, Rona Bremmer · European Journal of Pharmacology · 1979 · 419 citations · Full text

Medicine, Neuroscience, Pharmacology +6