Inhibition of p53 after acute myocardial infarction: Reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture

A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

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Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

Anique Ducharme, Stefan Frantz, Masanori Aikawa et al. · Journal of Clinical Investigation · 2000 · 805 citations · Full text

Heart Failure, Pathology, Biomedical Engineering +18

A mechanistic role for cardiac myocyte apoptosis in heart failure

Detlef Wencker, Madhulika Chandra, Khanh T. Nguyen et al. · Journal of Clinical Investigation · 2003 · 738 citations · Full text

Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice

Shin-ichiro Matsumura, Shiroh Iwanaga, Satsuki Mochizuki et al. · Journal of Clinical Investigation · 2005 · 322 citations · Full text

Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction

Shunji Hayashidani, Hiroyuki Tsutsui, Masaki Ikeuchi et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2003 · 314 citations