Ablation of Steroid Receptor Coactivator-3 Resembles the Human CACT Metabolic Myopathy

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

Christopher B. Newgard, Jie An, James R. Bain et al. · Cell Metabolism · 2009 · 3.1K citations · Full text

Insulin Resistance, Obesity, Metabolic Syndrome +12

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Timothy R. Koves, John R. Ussher, Robert C. Noland et al. · Cell Metabolism · 2008 · 1.9K citations · Full text

Metabolic Syndrome, Energy Metabolism, Mitochondrial Function +10

Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice

Javier Martı́nez-Botas, John Anderson, Darin Tessier et al. · Nature Genetics · 2000 · 576 citations

Obesity, Metabolic Syndrome, Nutrition +10

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

Jianming Xu, Lan Liao, Guang Ning et al. · Proceedings of the National Academy of Sciences · 2000 · 534 citations · Full text

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

Jie An, Deborah M. Muoio, Masakazu Shiota et al. · Nature Medicine · 2004 · 449 citations

Animal Physiology, Metabolic Syndrome, Hepatology +15