PLoS Biology · 2011 · 238 citations · 244 references
Life SciencesBioinformaticsGeneticsGenomic InformaticsGenomicsMetagenomicsGenome SequencingGenomic Data IntegrationGenomic DatabasesMetagenomic AnalysisMetagenomic Data Quality ControlData Standardization In GenomicsGenome Metadata ManagementInteroperable Genomic Data ModelsMetadata HarmonizationOpen Membership
A vast and rich body of information has grown up as a result of the world's enthusiasm for 'omics technologies. Finding ways to describe and make available this information that maximise its usefulness has become a major effort across the 'omics world. At the heart of this effort is the Genomic Standards Consortium (GSC), an open-membership organization that drives community-based standardization activities, Here we provide a short history of the GSC, provide an overview of its range of current activities, and make a call for the scientific community to join forces to improve the quality and quantity of contextual information about our public collections of genomes, metagenomes, and marker gene sequences.
244
Basic local alignment search tool
Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations
MUSCLE: multiple sequence alignment with high accuracy and high throughput
R. C. Edgar · Nucleic Acids Research · 2004 · 46.5K citations · Full text
Gene Ontology: tool for the unification of biology
Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text
Prodigal: prokaryotic gene recognition and translation initiation site identification
Doug Hyatt, Gwo-Liang Chen, Philip LoCascio et al. · BMC Bioinformatics · 2010 · 13.1K citations · Full text