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The Baylis-Hillman Bromides as Versatile Synthons: A Facile One-Pot Synthesis of Indolizine and Benzofused Indolizine Frameworks
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2009
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Facile One-pot SynthesisDerivativesVersatile SynthonsHeterocyclicNitrogen YlidesInteresting StrategyOrganic ChemistryBaylis-hillman BromidesChemistryHeterocycle ChemistryPharmacologyIndolizine FrameworksSynthetic ChemistryEnantioselective Synthesis
A facile one-pot synthesis of indolizine, benzofused indolizines {pyrrolo[1,2-a]quinoline and pyrrolo[1,2-a]isoquinoline} derivatives from the Baylis-Hillman (B-H) bromides, via an interesting strategy involving 1,5-cyclization of nitrogen ylides has been described.