Determination of the R(−)- and S(+)-enantiomers of γ-vinyl-γ-aminobutyric acid in human body fluids by gas chromatography—mass spectrometry

γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE¹

Michael J. Jung, Bruce Lippert, Brian W. Metcalf et al. · Journal of Neurochemistry · 1977 · 479 citations

Life Sciences, Biochemistry, Pharmacology +17

4‐Amino‐hex‐5‐enoic Acid, a Selective Catalytic Inhibitor of 4‐Aminobutyric‐Acid Aminotransferase in Mammalian Brain

Bruce Lippert, Brian W. Metcalf, Michel J. Jung et al. · European Journal of Biochemistry · 1977 · 379 citations · Full text

Life Sciences, Biochemistry, Biocatalysis +15

Huntington's Chorea

S.J. Enna, Edward D. Bird, James P. Bennett et al. · New England Journal of Medicine · 1976 · 181 citations

Life Sciences, Neurobiology, Neuroscience +16

Gas chromatographic—mass spectrometric analysis of optically active metabolites and drugs on a novel chiral stationary phase

Hartmut Frank, Graeme Nicholson, Ernst Bayer · Journal of Chromatography B Biomedical Sciences and Applications · 1978 · 172 citations

Pharmacy, Chemistry, Pharmaceutical Analysis +13

Increased gamma-aminobutyric acid (GABA), homocarnosine and β-alanine in cerebrospinal fluid of patients treated with γ-vinyl GABA (4-amino-hex-5-enoic acid)

Jeffrey Grove, Paul J. Schechter, G. Tell et al. · Life Sciences · 1981 · 119 citations

Life Sciences, Neuroscience, Pharmacology +15