In vivo anti-tumor effect of PEG liposomal doxorubicin (DOX) in DOX-resistant tumor-bearing mice: Involvement of cytotoxic effect on vascular endothelial cells

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

Gilad Haran, Rivka Cohen, Liliana K. Bar et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1993 · 920 citations

Natural Sciences, Biochemistry, Biophysics +16

Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial.

Donald W. Northfelt, Bruce J. Dezube, James Thommes et al. · Journal of Clinical Oncology · 1998 · 642 citations

Medicine, Oncology, Pharmacology +16

Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor

Eun Seong Lee, Kun Na, You Han Bae · Journal of Controlled Release · 2005 · 571 citations

Pharmacy, Molecular Pharmaceutics, Pharmacology +14

Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.

Dorit Goren, Aviva T. Horowitz, Dina Tzemach et al. · PubMed · 2000 · 402 citations

Pharmacy, Pharmaceutics, Pharmacology +17