Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death

The Serine Protease Omi/HtrA2 Regulates Apoptosis by Binding XIAP through a Reaper-like Motif

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Life Sciences, Cell Biology, Molecular Biology +17

Age and Outcome With Contemporary Thrombolytic Therapy

Harvey D. White, Gabriel I. Barbash, Robert M. Califf et al. · Circulation · 1996 · 274 citations

Medicine, Cardiology, Geriatric Medicine +17

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats

Jan Kajstura, Wei Cheng, P. Li et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1996 · 273 citations

Medicine, Cardiology, Pathology +11

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

Yasuyuki Suzuki, Kazuko Takahashi-Niki, Tomonori Akagi et al. · Cell Death and Differentiation · 2003 · 176 citations

Life Sciences, Cell Biology, Molecular Biology +16

miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia

Chad Siegel, Jun Li, Fudong Liu et al. · Proceedings of the National Academy of Sciences · 2011 · 173 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17