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Predicting the Effect of Cytochrome P450 Inhibitors on Substrate Drugs: Analysis of Physiologically Based Pharmacokinetic Modeling Submissions to the US Food and Drug Administration

Cytochrome P450 InhibitorsPhysiologically Based PharmacokineticsPharmacokinetic ModelingBiochemistrySubstrate DrugsMedicineDrug DiscoveryPharmacological StudyUs FoodToxicologyMetabolomicsPharmacologyPhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic ModelingDrug Resistance