Concepedia

3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity

Matthew J. Fisher, Ryan T. Backer, Vanessa Barth, Kim E. Garbison, Joseph M. Gruber, Beverly A. Heinz, Smriti Iyengar, Sean P. Hollinshead, Anne Kingston, Steven L. Kuklish,

Bioorganic & Medicinal Chemistry Letters · 2012 · 29 citations · 25 references

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25

CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding

Stephane Litschig, F. Gasparini, D Rueegg et al. · Molecular Pharmacology · 1999 · 343 citations

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Efficacy of Duloxetine, a Potent and Balanced Serotonin-Norepinephrine Reuptake Inhibitor in Persistent Pain Models in Rats

Smriti Iyengar, Amy A. Webster, Susan K. Hemrick-Luecke et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 293 citations

, , +17

Identification of a high-affinity binding site involved in the transport of endocannabinoids

Steven A. Moore, George G. Nomikos, Amy K. Dickason-Chesterfield et al. · Proceedings of the National Academy of Sciences · 2005 · 163 citations · Full text

, , +15

Dopamine D 2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats

Marie-Louise G. Wadenberg, Shitij Kapur, Alexandra Soliman et al. · Psychopharmacology · 2000 · 160 citations

, , +16

Knockdown of spinal metabotropic glutamate receptor 1 (mGluR<sub>1</sub>) alleviates pain and restores opioid efficacy after nerve injury in rats

Marian E. Fundytus, Kiran Yashpal, Jean‐Guy Chabot et al. · British Journal of Pharmacology · 2001 · 125 citations · Full text

, , +17