Agonist/antagonist properties of nalbuphine, butorphanol and (−)-pentazocine in male vs. female rats

Kappa–opioids produce significantly greater analgesia in women than in men

Robert W. Gear, Christine Miaskowski, Newton C. Gordon et al. · Nature Medicine · 1996 · 456 citations

Medicine, Anesthesiology, Pharmacology +13

[3H]U-69593 a highly selective ligand for the opioid κ receptor

Robert A. Lahti, Mary M. Mickelson, John M. McCall et al. · European Journal of Pharmacology · 1985 · 446 citations

Medicine, Medicinal Chemistry, Pharmacology +14

The kappa opioid nalbuphine produces gender- and dose-dependent analgesia and antianalgesia in patients with postoperative pain

Robert W. Gear, Christine Miaskowski, Newton C. Gordon et al. · Pain · 1999 · 273 citations

Medicine, Anesthesiology, Pharmacology +17

Gender difference in analgesic response to the kappa-opioid pentazocine

Robert W. Gear, Newton C. Gordon, Philip H. Heller et al. · Neuroscience Letters · 1996 · 234 citations

Medicine, Pharmacology, Gender +13

A kappa opioid effect: increased urination in the rat.

J. David Leander · Journal of Pharmacology and Experimental Therapeutics · 1983 · 226 citations

Medicine, Neuroscience, Pharmacology +16