Concepedia

Direct and Site‐Selective Palladium‐Catalyzed C‐7 Acylation of Indolines with Aldehydes

Youngmi Shin, Satyasheel Sharma, Neeraj Kumar Mishra, Sangil Han, Jihye Park, Hyunji Oh, Jimin Ha, Hyunwu Yoo, Young Hoon Jung, In Su Kim

Advanced Synthesis & Catalysis · 2015 · 69 citations · 62 references

DOI

Concepts

Abstract

Abstract The palladium‐catalyzed oxidative acylation of indolines at the C‐7 position with aldehydes or alcohols via CH bond activation is described. This protocol represents a facile access to 7‐acylated indolines, which can be readily transformed into 7‐acylated indoles with diverse biological properties. magnified image

References

62

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Barry M. Trost, Megan K. Brennan · Synthesis · 2009 · 1.1K citations

, , +11

Oxidative C−H Activation/C−C Bond Forming Reactions:  Synthetic Scope and Mechanistic Insights

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Transition Metal‐Catalysed, Direct and Site‐Selective N1‐, C2‐ or C3‐Arylation of the Indole Nucleus: 20 Years of Improvements

Lionel Joucla, Laurent Djakovitch · Advanced Synthesis & Catalysis · 2009 · 481 citations

, , +12